Pathogenicity of a reovirus type 2 in suckling mice: Insulitis and lymphoid atrophy.

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The active form of vitamin D, 1,25(OH)2D3, can prevent various forms of experimentally induced autoimmune disorders. The aim of this study was to confirm these findings in NOD mice that spontaneously develop an autoimmune type of diabetes mellitus. Therefore, the effect of a long-term 1,25(OH)2D3 treatment on the incidence of insulitis, the histological lesion preceding diabetes, was studied. F...

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ژورنال

عنوان ژورنال: The Japanese Journal of Veterinary Science

سال: 1989

ISSN: 0021-5295,1881-1442

DOI: 10.1292/jvms1939.51.1071